What’re Pseudoephedrine and side effects?
Pseudoephedrine is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes. It may be used as a nasal/sinus decongestant, as a stimulant, or as a wakefulness-promoting agent in higher doses. Wikipedia
Pseudoephedrine / Pseudo Ephedrine from / into Dole’s ephedrine (Pseudoephedrine) or medicines that are commonly known in the trade name Maxis Fed ( Maxiphed ), ACTIVATE Fed / L. Fed Apocalypse ( Actifed ), Ana Solis at ( Nasolin ), Nasi Fed ( Nasifed ), Sullivan, Dean ( Sulidine.) Is a medication to relieve nasal congestion, runny nose from colds, sinusitis and other respiratory allergies, with both single and mixed drugs, such as antihistamines, cough medicine, painkillers, etc.
Formulated with a combination of Sudo Ephedrine and Triprolidine antihistamines. (Triprolidine) due to the combination of Sudo Ephedrine with antihistamines Because antihistamines are effective in reducing mucus. But has very little anti-stuffy effect. Therefore, it must be mixed with Sudo ephedrine to allow the medication to have a nasal congestion effect.
Sudo ephedrine is absorbed quickly. The drug will begin to work within 15-30 minutes. Plasma drug concentrations will peak after approximately 30-60 minutes after taking the drug and will have a duration of 4-6 hours. Some drugs will be converted to the liver. Norpseudoephedrine Which is still active. The drug is excreted in the urine in a unchanged form, approximately 70-90% and in the form of Norpseudoephedrine, about 1-6% (the drug will be excreted more slowly. In the case of urine is alkaline)
With Sudo ephedrine, it can be used as a precursor in amphetamine production. The Ministry of Public Health has therefore restricted Sudo-ephedrine drugs to be used only in hospitals and the hospital must send a report of the purchase and dispensing of medicines to the patients every year with the Ministry of Public Health. Therefore, in modern pharmacies there is no longer a formula containing ephedrine Sudo available in pharmacies.
Forms and examples of ephedrine ephedrine
- Single-dose tablets of 30 or 60 milligrams and 120 or 240 milligrams, which are long-acting. There are trade names such as Maxiphed, Pseudoephedrine Asian Farms (Maxiphed). Pharm), Pseudoephedrine BJ Benjaosoth, Pseudoephedrine Medicine Products, Pseudoephedrine Medica Panno (Pseudoephedrine Milano), Sudo Ephedrine 60 mg (Pseudoephedrine 60 mg), Sudo Ephedrine Hydrochloride 60 mg and Iron tablets (Pseudoephedrine hcl 60 mg. Tablet) , into Donovan -30 (Pseudono-30), into Donovan -60 (Pseudono-60), Dana Sue Fed (Sudafed), Sudoku Master (Sudosain) and so on.
- Single dose syrup , 30 milligrams / teaspoon (5 ml), with examples of trade names such as Pseudoephedrine Asian Pharm.
- Compound tablets, such as a combination between Sudo ephedrine (Pseudoephedrine) 60 milligrams and anti-alloprolidine. (Triprolidine) 2.5 milligrams per 1 tabletThere are examples of trade names such as A-fed, Actil, Actiplex, Acmedine, Actifed / Actifed), Adulfed tablets, Cofed, Colidin tablets, Consudine, Decolfed, Pharma Fafed, Hiscifed tablets, KB Pophedin, Medifed, Medofed, Nasifed , Nasolin, Nostrilet, Polyfed tablets, Pondactil, Prophed, Profe. Prophedin, Rhinofed, Solodane, Solophed, Sulidine, Sufed, Tipo tablet ), Triofed, Tripogen, Trifed, Triprodrine, Trisudine tablets, Trisudine tablets Trisodine tablets, Utifed,
- Syrup such as seperated ephedrine (Pseudoephedrine) 30 mg and antihistamines, tri-propylidine (Triprolidine) 1.25 milligrams per 1 teaspoon (5 ml)There are examples of trade names such as Actifed syrup, Actil, Actiplex syrup, Coldifed syrup, Colidine. syrup, Confed syrup, Consudine syrup, Decolfed syrup, Fafed syrup, Hiscifed, Medifed Medifed syrup, Milafed syrup, Nasifed syrup, Nasolin syrup, Nostrilet syrup, Paxifed syrup ( Pacifed syrup, Policol syrup, pro Profed syrup, Prophedin, Rhinofed syrup, Sinusaid syrup, Sulidine syrup, Sufed syrup , Suphedrine syrup, Trifed syrup, Triofed syrup, Trisodine syrup,
- Sudo Ephedrine Single Drug (Pseudoephedrine)
- Helps relieve nose congestion or sinus caused by colds. Cold symptoms with a high runny nose, sinusitis, influenza, hay fever and other respiratory allergies
- Helps to relieve tinnitus and relieve ear pain caused by changes in air pressure during air travel or diving
- Helps to alleviate tinnitus or noisy symptoms in the ears due to Eustatian stenosis in allergies.
- Used together with other drugs to treat otitis media. Sudo-ephedrine can reduce the swelling around the Eustatian ostia, causing the Eustatian tube to become clogged, which will reduce bacterial infections of the middle ear.
- Medication between sudos and ephedrine nasal congestion (Pseudoephedrine) with antihistamines, triprolidine.
- Helps to relieve runny nose (runny nose), tearing, itchy nose and throat, coughing, sneezing, rash, urticaria and other allergic symptoms such as allergic rhinitis / hay fever (hay fever). Hay fever) and cure cold symptoms.
- Sudo ephedrine, both monotherapy and combination medicine, may be used to treat diseases or other conditions. If in doubt, ask a doctor or pharmacist.
Before using Sudo Ephedrine
When prescribing all medicines, including Sudo Ephedrine Things to notify your doctor or pharmacist are as follows:
- History of drug allergy to Sympathomimetic Group Sympathomimetic drug such as Ephedrine, Pseudoephedrine, Salbutamol, Terbutaline etc. or any component in This drug and allergy history for all other medicines, including drug allergy symptoms, such as taking more nausea, rash or tightness, difficulty breathing / difficulty breathing, etc.
- Drugs that are prescribed or prescribed by a doctor Including vitamin supplements and various herbal medicines that are currently being used or are about to be used Because Sudo-ephedrine drugs may cause the symptoms of the disease to exacerbate. Or may interact with other drugs and / or other supplements that are taken beforehand (In some cases it is not possible to use drugs that interact with each other at all. But in some cases it may be necessary to use those 2 drugs together Even though drug interactions can occur In which case the doctor will adjust the dose Or be more careful in giving the patient more appropriate medication) such as
- The use of Sudo ephedrine with central nervous stimulation Sudo-ephedrine enhances nerve stimulation, causing anxiety, insomnia, convulsions, and arrhythmia.
- The combination of Sudo-ephedrine and certain antihypertensive drugs, such as Alprenolol, can reduce the effectiveness of antihypertensive drugs  and need to be adjusted. Of the antihypertensive drug appropriately
- The combination of Sudo-Ephedrine and Group Drug beta-adrenergic blocking agents may increase the risk of high blood pressure, bradycardia, and heart blocks.
- The combination of Sudo-ephedrine and Digitalis glycosides increases the risk of cardiac arrhythmia. If required, they must be monitored and monitored closely.
- The combination of Sudo-ephedrine and Levodopa increases the risk of cardiac arrhythmia, therefore reducing the dose of Sudo-ephedrine
- The use of Sudo Ephedrine with certain epilepsy drugs such as acetazolamide (Acetazolamide) will increase the toxicity of Sudo Ephedrine.
- The combination of Sudo-ephedrine and Thyroid hormones increases the risk of heart failure. Patients with coronary artery disease should adjust the dosage appropriately.
- Combined medication (Pseudoephedrine + Triprolidine) with oral potassium chloride Will stimulate gastrointestinal irritation to the point of ulcers occur, Sodium oxybate will result in increased side effects of tri-propylidine, such as Dizziness and extreme sleepiness. Confusion and depression. There may be low blood pressure in some people. And may experience symptoms of coma and eventually death. Propoxyphene can increase the side effects of tri-propylidine, such as dizziness, drowsiness, confusion, and may affect the nervous system, so you should avoid using these drugs together.
- Having or ever having underlying diseases such as coronary artery disease, asthma, emphysema, heart disease, high blood pressure, diabetes, glaucoma, liver disease, kidney disease, enlarged prostate. Difficulty urination, epilepsy, thyroid abnormalities, toxic goiter.
- If it’s a lady Should inform that she is pregnant Or planning a pregnancy Or is breast-feeding Because many drugs can pass through the placenta or milk and enter the baby to cause side effects to the baby.
When forgetting to take Sudo Ephedrine
In general, Sudo Ephedrine is only used when symptoms occur. So forgetting to take the drug is not dangerous. But if having to take the medication on schedule and forget to take the medicine Take the medicine as soon as he can remember But if the time is similar to the next meal Skip to the next medication immediately Without having to increase the dose to 2 times or more normal.
Side effects of ephedrine ephedrine
- Can stimulate chest pain There may be a reverse effect, causing more mucus when the drug is stopped. Chills, confusion, anxiety, loss of direction, hallucinations, insomnia, panic, nervousness, inflammation, restlessness, sweating, headache, dizziness, house rotation, ringing in the ears, blurred vision, blurred vision, nausea, discomfort, constipation Diarrhea, vomiting, dry mouth, dry throat, dry nose, stuffy nose, accumulation of bronchial secretions, shortness of breath Irregular shortness of breath, palpitations, irregular heartbeat Tachycardia, emphysema, temporary high blood pressure Can experience bleeding in the skull, difficulty urinating, urinary retention, difficulty urinating or pain while urinating Blood transfusion or stomach ache Numbness of hands, feet, trembling hands, trembling, skin sensitive to light, rash, hives
- Sudo ephedrine is a drug that can stimulate the brain to wake up. Makes not sleepy Insanely Out of control Therefore this drug has been used in the wrong way By being used as a mixture of stimulants in athletes Used as a drug for diligence and as amphetamines
- The symptoms of overdose of ephedrine are fast breathing, high blood pressure. Irregular heart beat The heart beats fast or slow, trouble breathing, fears, restlessness, hallucinations, convulsions.
- For Triprolidine Compound Possible side effects include drowsiness, dry mouth, loss of appetite, nausea, vomiting, headache, dizziness. Restless, blurred vision, heartburn, chest pain, constipation, stomach discomfort, excessive urination, urinating, etc. The overdose Can cause hallucinations, convulsions, coma to the point of death When such symptoms occur, the patient must be rushed to the hospital immediately.