Abacavir is a nucleoside reverse transcriptase inhibitors (NRTI) antiviral drug used by doctors in combination with other HIV medicines. Effectively reduces the number of HIV infection in the body of infected patients. Which helps the immune system work better It also reduces the risk of complications from HIV, such as other infections and cancer, and may be used to treat other conditions at the doctor’s discretion.
|Drug group: Antiviral drugs in the NRTI group|
Drug type: Prescription drugs
Properties: It reduces the number of HIV infection in the body of infected patients.
Patient group: Adult or child
Dosage form: Oral medicine
Use of the drug in pregnant women: Category C animal studies found that Cause abnormalities to the fetus in animals But no human studies Or there is not enough data in human and animal studies. Should be used when considering that There are benefits outweigh the potential risks to the fetus.
Warnings for using abacavir:
- Let your doctor know before using this drug. If you have a history of drug allergy or any component of this drug Also, if you are allergic to drugs and other substances, this drug may contain ingredients that can cause allergic reactions or cause other side effects.
- Tell your doctor about medications, vitamins or herbal All patients were using a particular drug, methadone and drug treatment of infectious HIV, other types because some drugs may interact with medications and cause. Side effects or make the drug less effective
- Let your doctor know before using the drug. If the patient has heart disease High blood pressure Liver disease, such as hepatitis B and C, or cirrhosis of the kidneys, there are risk factors for heart disease like smoking. Have diabetes or have High cholesterol And have used drugs to treat HIV infection
- Patients using this drug may be at risk. Towards the occurrence of ischemic heart disease more You should always consult your doctor about the advantages and disadvantages of the drug before taking it.
- This drug should not be used if the patient has moderate to severe liver disease. Or if the patient carries the HLA-B * 5701 allele, as there is a risk of serious drug allergy.
- This drug should not be used in combination with other HIV medicines that already contain Abacavir.
- Talk to your doctor before using any medication, as Abacavir may cause lactic acidosis, especially women or people who take HIV medication for a long time.
- Do not start the medication, stop using the medication, skip the medication, or change the dosage by yourself without your doctor’s advice. Because it may cause the virus to multiply The infection is difficult to treat. And the side effects worsened
- People may need frequent medical tests while using this drug. To monitor symptoms and check for possible side effects
- Avoid drinking alcohol Because it may increase the risk of liver damage even more
- Do not have unprotected sex. And do not share razors or toothbrushes with others Because the drug does not stop the transmission of HIV to others.
- HIV-infected patients who are pregnant should discuss the pros and cons before using the drug. And use drugs strictly as prescribed by the doctor To reduce the risk of infection from mother to child
- HIV-infected patients should not breastfeed while using this drug. Because the drug may penetrate into the mother’s milk and harm the baby
Dosage for Abacavir:
Dosage and duration of use are at the discretion of the treating physician. With an example of using drugs as follows:
Examples of drugs treating infected with HIV.
take 300 mg twice / day or 600 mg once / day in combination with other antiretroviral drugs.
- Aged 3 months and over with body weight 14-20 kg take 150 mg twice / day or 300 mg 1 time / day.
- Children over 3 months, weighing 20-25 kg, take 150 mg in the morning and 300 mg in the evening or 450 mg once / day.
- Children aged 3 months and over with a body weight of 25 kg or more. Take the same amount of medication as adults.
Side effects from Abacavir:
Abacavir can usually cause side effects such as sleep problems, strange dreams, headache, tiredness, fever, chills, feeling sick, nausea, vomiting, rash, or, in children, often stuffy nose, sneezing, and sore. Neck and ear pain etc.
The patient should stop taking the drug and see a doctor. If you encounter an allergic reaction such as
- Fever with a rash
- Nausea, vomiting, diarrhea, abdominal pain
- Feel sick Extremely tired Body aches
- Shortness of breath
- Cough and sore throat
Serious side effects that are not a sign of an allergic reaction to Abacavir are severe upper abdominal pain, nausea, vomiting, loss of appetite, swelling of the trunk area. Dark urine Pale stools, jaundice, unusual tiredness, chest pain, tightness and pain that spreads to the jaw or shoulder.