Acanthosis Nigricans is a condition in which the skin around the folds of the body turns dark brown and the skin becomes thicker than usual. It is usually found under the armpits, neck, or groin. It is more common in adults with obesity or diabetes. and children at risk of type 2 diabetes
Acanthosis Nigricans can be a sign of a serious disease. like diabetes In some cases, it may be a sign of cancer of the liver or stomach, but is relatively rare. If treated according to the cause of the disease properly, symptoms on the skin can be improved. Therefore, the patient should see a doctor for proper diagnosis and treatment.
Symptoms of Acanthosis Nigricans
Acanthosis Nigricans usually has no symptoms other than noticeable symptoms on the skin. which will cause dark brown blotches looks like velvet and the skin is thicker than other areas Blemishes are often found in various folds of the body, including the back of the neck, under the armpits, the crook of the arms and legs, the groin, the knuckles, the lips, the palms and the soles of the feet.
In some cases, there may be an itchy or foul smelling sensation from the affected skin area. Symptoms of Acanthosis Nigricans usually develop slowly, but if any changes are noticed on the skin, especially when the onset of the disorder progresses quickly, it may occur. You should see your doctor for treatment.
Causes of Acanthosis Nigricans
Acanthosis Nigricans occurs because the body rapidly produces new skin cells with a high amount of pigment.
It is a condition that can be found in all genders and ages. And it can be found in both healthy people or people with certain health conditions. especially the following health problems.
- Insulin Resistance Insulin is a hormone produced by the pancreas. It is responsible for bringing sugar into cells for energy in the body. If you have insulin resistance Your body is less responsive to insulin. As a result, blood sugar levels build up and can lead to type 2 diabetes.
- Hormonal disorders, such as Polycystic Ovary Syndrome, Hypothyroidism, Cushing Syndrome, and Addison’s Disease, a disorder of the adrenal glands. kidney, etc.
- pituitary gland disorder
- Use of certain medications, such as birth control pills and thyroid medication corticosteroids Drugs that reduce side effects from chemotherapy, human growth hormone and large amounts of vitamin B3, etc.
- Certain cancers, such as lymphoma Stomach cancer, colon cancer and liver cancer, etc.
In addition, other risk factors that may trigger these symptoms include:
- Obesity was found that if the more weight. Your risk of developing symptoms may be even higher.
- Inheritance from a family member who has a history of the condition
- Ethnicity: It is most common in people of Central and South American, African, and Caribbean races.
- Skin color is more common in blacks than whites.
Diagnosis of Acanthosis Nigricans
Acanthosis Nigricans is a condition in which the abnormal symptoms are usually only visible on the skin. The diagnosis was made using a questionnaire. the patient’s health history and inquire about medications or dietary supplements In addition to medications prescribed by a doctor
In addition to the initial examination of the affected skin area In case of suspected diabetes or insulin resistance Your doctor may diagnose it by measuring your blood sugar. Or measure blood sugar levels after fasting (Fasting Insulin Test), but if the cause of the disease is not clear. Your doctor may make an additional diagnosis, such as an X-ray or taking a tissue sample from the affected skin for a lab test (Skin Biopsy).
Acanthosis Nigricans Treatment
Although Acanthosis Nigricans is not a disease, it is an uncommon condition that should be diagnosed and treated. The goal is to focus on treatment according to the cause that caused the symptoms. and causing the skin that has an abnormally dark color to gradually fade, which can be divided into treatment methods according to diseases or disorders of the patient’s body.
- weight loss to be within the normal range Diet and exercise regularly For those who are obese or those with a BMI of 30 or higher and those with diabetes. These methods may help treat Acanthosis Nigricans.
- Changing medications or refraining from taking medications and supplements that may affect symptoms
- Surgery in cases where a patient has cancerous cells in the body that may trigger Acanthosis Nigricans, which usually improves on the skin after surgery.
- Taking medication to treat the underlying disease, such as hormone therapy and insulin therapy.
In the event that the patient has itching feeling unwell or a foul odor on the affected skin Doctors prescribe different types of drugs or treat them with the following methods.
- Creamy topical creams that lighten and soften the skin, such as Retin-A, vitamin D, alpha hydroxy acid (AHA), salicylic acid. and 20 percent urea
- Antibacterial soap
- Oral medications such as antibiotics and acne medications
- Skin laser treatment to treat skin that is raised or abnormally thick
Complications of Acanthosis Nigricans
Complications from Acanthosis Nigricans can vary greatly depending on the cause. Some patients may be at risk of complications. like type 2 diabetes or some types of cancer
Prevention of Acanthosis Nigricans
This is because Acanthosis Nigricans is more common in people with obesity. An effective method of protection is Controlling and adjusting eating behavior By eating a wholesome diet, focusing on fruits, vegetables and whole grains. Avoid foods high in fat and sugar. exercise regularly and control the weight to be within the normal range This may help prevent obesity and other diseases that cause health problems.
You should also avoid taking birth control pills or other medications that may trigger symptoms. If you are a patient with underlying disease related to Acanthosis Nigricans such as hypothyroidism. should receive appropriate and continuous treatment